Bio-Pak® depth filter cartridges are specifically designed for critical applications to prevent bypass at the cartridge sealing surfaces. The first U.S. manufactured double O-ring filter element, the Bio-Pak® cartridge for the Pharmaceutical market provides a relatively high flow rate, positive electrical charge, and superior retention of ultra-fine particles. The Bio-Pak® filters are ideal for downstream processing of biopharmaceuticals, plasma fractionation and the bulk filtration of culture media, topicals and intermediates filtration.