High Temperature Sterilizing Grade Air and Gas Filters - HIGH FLOW TETPOR XT

HIGH FLOW TETPOR XT high temperature sterilizing grade air and gas filters provide reliable 0.2 micron sterile filtration of compressed air and process gases in demanding pharmaceutical and biopharmaceutical applications. These pleated cartridge filters combine an inherently hydrophobic expanded PTFE membrane with a robust high-temperature construction to maintain sterility even during extended high temperature operation.

Engineered specifically for gas sterilization, HIGH FLOW TETPOR XT cartridges are validated as sterilizing grade in liquid in accordance with ASTM F838 bacterial challenge testing, and have been shown effective for viral and bacteriophage retention. The large-bore stainless steel core and optimized pleat geometry deliver high flow rates at low pressure drop, supporting efficient sterile gas distribution and venting while minimizing energy consumption and filter change-out frequency.

To support continuous operation at elevated temperatures, the PTFE membrane is supported by polyphenylene sulfide (PPS) layers, with heat stabilized polypropylene hardware rated for continuous service up to 100 °C. The cartridges can be in situ steam sterilized for up to 120 cycles at 135 °C, making them ideal for systems that rely on frequent SIP regimes. Biocompatibility testing to USP <87> and USP <88> Plastics Class VI – 121 °C helps support their use in critical life science processes.

HIGH FLOW TETPOR XT sterilizing grade air and gas filters are available in 10 in, 20 in, and 30 in lengths with a 226 bayonet/fin end configuration and a range of O-ring materials, allowing easy integration into standard sanitary and industrial housings. Typical uses include high inlet air temperature lines and heated vent filters on storage tanks containing water for injection (WFI) or other elevated-temperature process fluids, as well as other critical sterile gas and vent applications in pharmaceutical and bioprocessing facilities.

Key Features

• 0.2 micron expanded PTFE membrane for sterilizing grade air and gas filtration
• Validated bacterial retention in accordance with ASTM F838 for sterility assurance
• Inherently hydrophobic membrane for reliable performance in air and gas service
• Heat stabilized construction enables continuous operation up to 100 °C
• In situ steam sterilizable for up to 120 cycles at 135 °C
• Polyphenylene sulfide support layers and stainless steel core for high mechanical strength
• Large effective filtration area (0.7 m² per 10 in) for high flow and low pressure drop
• Available in 10 in, 20 in, and 30 in cartridge lengths
• 226 O-ring/fin end configuration for secure sealing in compatible housings
• Multiple O-ring materials (silicone, EPDM, FEP-encapsulated silicone, Viton) to match process compatibility needs

Typical Applications

HIGH FLOW TETPOR XT filters are designed for high temperature sterile gas and vent service in critical life science environments. Typical applications include:

• High temperature sterile air inlet and exhaust on pharmaceutical and biopharmaceutical processes
• Heated vent filters on WFI and purified water storage tanks (>80 °C contents)
• Sterile gas filtration for process tanks, reactors, and transfer vessels
• Sterile barrier filtration for compressed air and nitrogen utilities supplying critical equipment
• Sterile venting on autoclaves and other high temperature process equipment (within specified limits)

Note: TETPOR and DEMICAP are registered trademarks of Parker Hannifin Corporation