MabTec^® Automated Cell Culture Maintenance System

The Parker SciLog^® MabTec^® Automated Cell Culture Maintenance System from CLEAR Solutions is a compact, fully automated platform designed to simplify and standardize high‑density cell culture and bioreactor maintenance. This gravimetric, automated cell culture maintenance system enables safe, walk‑away operation so your team can focus on higher‑value activities while maintaining consistent bioreactor performance.

MabTec automatically feeds, harvests, and recirculates cell culture in either fully disposable or hybrid bioreactor flow paths. Pre‑programmed modes for bioreactor maintenance minimize setup time and reduce the risk of operator error, while dedicated modes for inoculation, transfection, and induction allow precise additions on repeated schedules or during off‑hours with no need for a constant physical presence.

The system supports both bolus and continuous feeding strategies for up to 100 days, and when coupled with a balance it can maintain a steady‑state bioreactor weight or volume. MabTec can also maintain fresh media in the reactor, remove harvest material, or prevent accumulation of waste products without requiring a scale under the bioreactor—providing a flexible platform for perfusion‑style operations and process intensification.

Built around Parker’s open‑architecture design philosophy, the MabTec system is available with a choice of pump heads and is compatible with virtually all bioreactors from 50 mL to 2000 L. This makes it easy to integrate into existing single‑use, stainless, or hybrid bioreactor trains in R&D, pilot, or GMP environments. Real‑time data collection and optimization tools support better process understanding, documentation, and technology transfer across sites.

Features

• Fully automated gravimetric cell culture maintenance system for high‑density cultures
• Safe, walk‑away bioreactor operation with reduced operator intervention
• Pre‑programmed modes for bioreactor maintenance, feeding, harvesting, and recirculation
• Dedicated modes for inoculation, transfection, and induction with precise, scheduled additions
• Supports bolus or continuous feeding strategies for up to 100 days of operation
• Capable of maintaining steady‑state bioreactor weight/volume when used with a balance
• Can maintain fresh media, harvest product, and manage waste without a scale under the reactor
• Open‑architecture design with choice of pump heads to fit your process requirements
• Compatible with bioreactors from 50 mL to 2000 L, including disposable and hybrid systems
• Real‑time data collection and optimization tools to support process monitoring and documentation

Bioreactor Compatibility

• Compatible with bioreactors from 50 mL to 2000 L
• Suitable for disposable, stainless steel, or hybrid bioreactor flow paths

Pre‑Programmed Modes

• Bioreactor maintenance
• Inoculation
• Transfection
• Induction