SciLog® NFF+ PM Manual NFF System with PUPSIT
Product Description
The SciLog® NFF+ PM represents a best-in-class, stand-alone normal flow filtration (NFF) solution for regulated bioprocessing environments. Engineered to enable both Pre-Use Post-Sterilization Integrity Testing (PUPSIT) and post-use integrity testing, the NFF+ PM system is specifically aligned with the EU GMP Annex 1 (2022) standards. Ideal for final fill and bulk filtration, it provides robust process security for manufacturers of pharmaceuticals, biologics, and advanced therapies.
With its intuitive manual control valves and upright manifold support, the NFF+ PM ensures hassle-free installation and operation in cleanroom settings. Its efficient design streamlines workflow—organizing tubing, minimizing air traps, and enhancing operator visibility throughout the process. The platform is fully mobile and castor-mounted, designed for simple integration alongside your existing GMP-compliant infrastructure.
The NFF+ PM requires external pressure monitors and pumps, allowing users to build a flexible, tailored solution. For processes demanding redundant filtration and added risk mitigation, the SciLog NFF+ PMR variant provides clear, segregated flow paths and dual filter support, all within a compact footprint.
Parker’s comprehensive support covers single-use manifold design, FAT/SAT, validation documentation, training, and integration consultation—ensuring optimal configuration for every application.
Features
- Stand-alone manual NFF skid with integrated PUPSIT capabilities
- Mobile, cleanroom-compliant platform (castor-mounted)
- Manual valve controls for secure operation
- Vertical manifold design for process visibility and component support
- Redundant filtration variant (NFF+ PMR) available for dual-filter processes
- Simple installation and easy integration into GMP environments
- Designed to minimize hold-up volume and air traps
- Supports both single-use and fixed membrane pressure sensors
- No pump included; flexible to user-preferred pump and instrumentation
- Closed system design for cleanroom applications
Specifications
| System Type | Manual sterilizing NFF skid (with PUPSIT) |
|---|---|
| Number of Product Filters | 1 (PM) or 2 (PMR) |
| Filter Size Range | 1” to 30” |
| Valve Control | Manual |
| Pressure Sensors | Single-use (in-line) or fixed/membrane options |
| Number of Pressure Sensors | 2 (PM), 4 (PMR) |
| SciPres® Monitors | 1 (PM), 2 (PMR) |
| Pump | Not included, user-supplied |
| Dimensions (W x H x D) | 1.2 x 1.9 x 0.7 m (PM), 1.5 x 1.9 x 0.7 m (PMR) |
| Redundant Filtration | Available (PMR variant) |
| Cleanroom Compatibility | Yes |